Research Roundtable May 3, 2022 | 8-9 am

Building a safety culture in the NICU

Jimmy Hu, PhD Candidate, Health Research Methodology

Supervisors: Drs. Lehana Thabane & Salhab el Helou

The McMaster Neonatal Intensive Care Unit is aiming to improve its safety culture, through a multi-pronged complex intervention. This talk will describe the components of this complex intervention, and how they drive change towards improving safety culture. Methodogic challenges will also be described, including the use of novel frameworks, and evaluating the dynamic intervention.


  1. Understand what is safety culture and the frameworks used to change safety culture.
  2. Understand that changing safety culture is a complex, dynamic and interdependent process.

Research Roundtable April 29, 2022 | 12-1 pm

Improving inhaled Nitric Oxide (iNO) use in a tertiary level NICU: decreasing cost and standardizing usage of iNO through quality improvement methodology

Dr. Jennifer Twiss, Assistant Professor, Division of Neonatology

Dr. Eman al Johani, Neonatal Perinatal Medicine fellow

Use of iNO in the preterm population for hypoxemic respiratory failure is controversial and currently off label.  After a chart review, our center was identified as having high rates of use of iNO in this population, therefore a quality improvement study was designed to decrease the off label usage of iNO and standardize our approach to using iNO, with the anticipated effect of decreasing the associated cost.


  1. Review the choices of QI tools and methodology used during this project.
  2. To discuss challenges in launching interventions that require testing prior to implementation, and seek feedback on how to move through these challenges

Research Roundtable April 5, 2022 | 8-9 am

Vaccination in Children with Special Needs

Dr. Emily Fong, PGY2

Supervisor: Dr. Ronit Mesterman

This study assesses vaccination rates in children with special needs, especially children with autism spectrum disorder (ASD) and intellectual disability (ID.) Vaccination rates in children with ASD and ID are affected by different factors, including behaviours such as aggression or anxiety. We want to assess which factors have had the most impact on children with special needs completing their vaccinations or refusing them. We are also hoping to learn what kinds of interventions have helped them to receive their required vaccines


This session will consider different barriers to vaccination for children with special needs.

Research Roundtable March 25, 2022 | 12-1 pm

Non-inferiority trials: What you need to know about what the are (not), pros and cons, why we use them, and how to appraise them

Dr. Lehana Thabane

Dr. Lehana Thabane is Vice President of Research at St Joseph’s Healthcare – Hamilton; Scientific Director of the Research Institute at St Joseph’s Healthcare; Professor of Biostatistics and former Interim Chair/Associate Chair of the Department of Health Research Methods, Evidence, and Impact; Associate Member of the Departments of Pediatrics, Medicine, Family Medicine, Surgery, Psychiatry and Behavioural Neurosciences, and Anesthesia, School of Nursing, and School of Rehabilitation Science in the Faculty of Health Sciences at McMaster University. He is also the Director of Biostatistics at St. Joseph’s Healthcare – Hamilton.

Research Roundtable March 1, 2022 | 8-9 am

Estimates of pediatric pneumonia incidence, morbidity, and mortality in developed countries since 2010: a systematic review and meta analysis

Dr. Kevin Karivelil, PGY2

Supervisor: Dr. Jeff Pernica

Pediatric pneumonia is a significant cause of morbidity and mortality worldwide, being responsible for the deaths of more than 800,000 children per year. Most of these deaths occur in the non-industrialized world; however, the incidence and burden of pneumonia in developed nations has not been recently well described. This presentation will outline the early stages of a systematic review, aiming to quantify the incidence and burden of pneumonia in high-income countries after the inclusion of 13-valent pneumococcal conjugate vaccines in universal immunization programs. The research question, search strategy, inclusion/exclusion criteria, and outcomes of interest will be shared for critical feedback.


  1. To recognize the paucity of recent data on pediatric pneumonia incidence/morbidity in high-income countries, and reflect critically about how new data might affect current antibiotic prescribing practices and/or health policy.
  2. To provide feedback on various methodological steps in this systematic review.

Research Roundtable February 18, 2022 | 12-1 pm

Developing the GENDER-Q Kids: Our approach to creating a patient-reported outcome measure for children and adolescents who are receiving gender-affirming care

Shelby Deibert, PhD(c)

Supervisor: Dr. Anne Klassen

Our team is developing a patient-reported outcome measure (PROM) for children and adolescents (ages 8-18) who are receiving gender-affirming care (called GENDER-Q Kids). To create the GENDER-Q Kids, we are using a multi-phased, mixed-mixed methods approach. This presentation will focus on our phase one qualitative study. This study involves exploring concepts important to children and adolescents who are receiving gender-affirming care and forming a conceptual framework and comprehensive set of independently functioning scales.


  1. To review the methods we are using in our phase one qualitative study.
  2. To invite feedback on engaging youth in virtual research and working with research advisory committees.

Research Roundtable February 1, 2022 | 8-9 am

Wellness Needs Assessment of Pediatric Trainees at McMaster Children’s Hospital

Dr. Claire Young, PGY2

Supervisor: Dr. Joanna Humphreys

While the importance of medical trainee wellness is being increasingly recognized, we continue to lack specific data from our medical trainee cohorts that can provide a detailed assessment of their overall well-being. Within this study, we aim to create a comprehensive survey to assess wellness needs within the McMaster pediatric trainee population, including residents and subspecialty fellows. Ultimately, we aim to identify key areas for wellness-focused intervention.


1. Review existing literature on medical trainee wellness

2. Identify and discuss key components of a comprehensive wellness needs assessment, using an appreciative inquiry method

The Efficacy of the 2019 McMaster Children’s Hospital Anaphylaxis Kits versus the Standard Anaphylaxis Kit

Dr. Meagan Kaye, PGY2

Supervisor: Dr. Ronish Gupta

Anaphylaxis is an acute, potentially life-threatening systemic allergic reaction to various triggers. There is international consensus that intramuscular epinephrine is the first line and most effective treatment for anaphylaxis. Despite this, it is commonly underutilized and misused by healthcare professionals. As part of a quality improvement initiative at McMaster Children’s Hospital (MCH), a new anaphylaxis kit was developed and implemented in 2019. Our aim is to showcase that the 2019 MCH kit results in fewer medication errors as it pertains to inpatient anaphylaxis management versus the standard anaphylaxis kit.


  1. To define anaphylaxis and anaphylaxis management
  2. To review why errors in anaphylaxis management occur and what has been implemented at MCH to decrease errors
  3. To outline our proposed methods to showcase the efficacy of the 2019 MCH anaphylaxis kit versus the standard anaphylaxis kit

Research Roundtable January 21, 2022 | 12-1 pm

EPIC Implementation – Research Overview

Presented by

Katie Porter, Director of Research Administration, Hamilton Health Sciences

Sasha Eskandarian, Manager, Research Compliance and Support Services, Hamilton Health Sciences

Korinne Hamilton, Coordinator, Compliance & Quality Assurance, Research Compliance and Support Services, Hamilton Health Sciences

In preparation for the June 4, 2022 go-live of EPIC at HHS, Odyssey Research Working Group Co-Chair (K Porter) and Working Group colleagues will provide an overview of the implementation process for research, how studies will be integrated into the system, as well as training and system access for research staff and stakeholders (such as monitors). Core session content from the HHS Research Community Town Hall held December 17, 2021 will be further enhanced by YOUR questions!

Investigators and research teams are encouraged to submit questions online by January 17th at noon.

Research Roundtable January 4, 2022 | 8-9 am

Prevalence of Intimate Partner Violence Among Canadian Adolescents: A Systematic Review

Dr. Kristen Salena, PGY2

Supervisors: Dr. Stacey Marjerrison, Dr. Gita Wahi, Dr. Rosheen Grady, Dr. Melissa Kimber

Much of the discourse around Intimate Partner Violence (IPV) focuses on adults as opposed to youth; however, adolescents are at particularly high risk of IPV. While there is evidence that these groups of adolescents are at disproportionately higher risk of IPV, there is a paucity of literature on IPV in these populations. There has been only one published study on the national prevalence of
adolescent dating violence in Canada and, to date, there are no systematic reviews examining prevalence of IPV among Canadian youth. Our aim is to perform a systematic review in an effort to consolidate evidence in this area. Ultimately, we hope to inform policy and practice for Canadian Pediatricians and trainees caring for youth at risk of IPV.


1) Define Intimate Partner Violence.

2) Review the current literature on IPV in adolescents.

3) Discuss research methodology as it pertains to conducting a systematic review.

Research Roundtable December 3, 2021 | 12-1 pm

TRansition-US-Together (TRUST) study: An educational toolkit to support adolescents with chronic disease and their parents as they transition to adult care

Dr. Michelle Batthish, Associate Professor & Division Head, Pediatric Rheumatology, Allergy & Immunology, Department of Pediatrics

The transition from pediatric to adult healthcare is a vulnerable period among patients with chronic disease.

Promotion of health self-efficacy and continuing attention to self-management is associated with better health-related quality of life.

Parents and caregivers face unique challenges as they struggle to define new roles and responsibilities in their child’s care.


1- To review the methodology addressing two of our study objectives.

2- Discuss how researchers should select outcomes to measure the impact of their intervention when no (validated) outcome measures exist.