Unraveling the Risk: According to current literature, what are the risk factors for developing psychosis among individuals with 22q11.2 deletion syndrome?
Dr. Alexandra Hul, PGY3
Supervisor: Dr. Elisabetta Trinari, Assistant Professor, Pediatrics, McMaster University
22q11.2 Deletion Syndrome is the most common microdeletion syndrome in humans, leading to multisystemic involvement. While the association between 22q11.2 DS and psychosis is well-documented, the reasons why some individuals with the syndrome develop psychosis and others do not is not as clear. This study is a scoping review aimed at identifying and categorizing risk factors associated with developing psychosis in those with 22q11.2 DS.
Learning Objectives:
1. Identify the clinical features and multisystem involvement of 22q11.2 Deletion Syndrome (22q11.2 DS)
2. Recognize the link between 22q11.2 DS and psychosis with an emphasis on impact on patient care
3. Invite discussion on scoping review methodology as it pertains to the research question
macpedsrrt.ca 